Readers of Science magazine voted Synthorx technology as the 2014 “People’s Choice for Breakthrough of the Year.” The advancement, nicknamed “Giving life a bigger genetic alphabet,” was published in the journal Nature in May 2014.
The genetic alphabet (DNA sequence) is normally made up of four bases, abbreviated A, T, C, and G. Our technology adds two new synthetic bases, which we call X and Y. The incorporation and replication of X and Y into DNA means that, for the first time, live bacterial cells can be used to produce a much wider variety of proteins than they normally would—proteins that can be used as medicines, vaccines, diagnostics, nanomaterials, and more.
Several news outlets highlighted this recognition, including U-T San Diego. In that article, Synthorx CEO Court Turner explained that we are very close to making proteins with these partially synthetic bacteria.